Protein response is a field of research that focuses on how cells and organisms respond to changes in their environment by altering the expression and function of proteins. This response is critical for maintaining cellular homeostasis and adapting to different stressors, such as heat, cold, toxins, or nutrient deprivation. The protein response pathway involves complex signaling networks that regulate the synthesis, folding, trafficking, and degradation of proteins in order to protect cells from damage and promote survival. Understanding the mechanisms underlying protein response can provide insights into various diseases and potential therapeutic targets.